Measuring Myelin Integrity: Coming of Age in Preclinical and Clinical Arenas
Journal: ASN Neuro
By the turn of the twentieth century, major questions about cell form and function in the peripheral nervous system (PNS) and central nervous system (CNS) were moving beyond simple considerations of cell size and morphology to structure and function. One such consideration was the relationship between the axonal projections of medium and large peripheral neurons and the birefringent wrapping of medullated nerves (my…