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Current call-for-papers opportunities for Drug Design, Development and Therapy. Ranking signals: Indexed (Active), JIF 5.1. Use the official publisher page to verify scope and submission rules.
Journal: Drug Design, Development and Therapy
Often referred to as the "guardian of the genome", p53 plays an important role in maintaining cellular homeostasis by regulating and orchestrating cell cycle arrest, DNA repair, apoptosis, and senescence. Mutations in the TP53 gene which encodes p53, are found in a broad range of human cancers, leading to loss of its tumor-suppressive functions and contributing to cancer progression and metastasis. In addition, some…
Journal: Drug Design, Development and Therapy
With the emergence of fragment-based drug discovery (FBDD), the field of drug discovery has undergone significant changes. Unlike traditional high-throughput screening techniques, FBDD is based on identifying low molecular weight compounds (fragments) with a low affinity to the biological target. These initial fragment hits are then developed into drug-like molecules through a range of techniques, including fragment…
Journal: Drug Design, Development and Therapy
The development of advanced drug delivery systems is essential for improving the efficacy and shelf-life of sensitive biomolecules, including proteins, peptides, and nucleic acids. Among emerging technologies, sol gel-derived hybrid materials, particularly silica-based matrices, have gained prominence as versatile platforms for therapeutic stabilization and delivery. These materials offer mild synthesis conditions,…
Journal: Drug Design, Development and Therapy
Cancer immunotherapy has fundamentally transformed the treatment landscape of multiple malignancies. Immune checkpoint inhibitors, cellular therapies, cancer vaccines, and novel immune-modulating agents have produced durable responses across a broad range of solid tumors and hematologic malignancies. Over the past decade, immunotherapy has evolved from a promising experimental approach into a cornerstone of modern o…
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