Immunological risk stratification in highly sensitized transplant candidates: integrating molecular matching, crossmatching, donor selection, and desensitization
Deadline 2027-03-02FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Highly sensitized transplant candidates continue to face significant barriers to transplantation because of pre-existing antibodies against donor HLA antigen...
Immunological risk stratification in highly sensitized transplant candidates: integrating molecular matching, crossmatching, donor selection, and desensitization
Deadline 2027-03-02FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Highly sensitized transplant candidates continue to face significant barriers to transplantation because of pre-existing antibodies against donor HLA antigen...
Complex human in vitro models in immunology: advancing translational research and disease modelling
Deadline 2027-03-04FrontiersIndexed (Active)
Journal: Frontiers in Immunology
This collection will highlight the expanding role of complex human in vitro models in immunology research, with a focus on how these systems improve mechanis...
Complex human in vitro models in immunology: advancing translational research and disease modelling
Deadline 2027-03-04FrontiersIndexed (Active)
Journal: Frontiers in Immunology
This collection will highlight the expanding role of complex human in vitro models in immunology research, with a focus on how these systems improve mechanis...
Advancing allogeneic transplantation through multi-donor, immunotherapy, and precision strategies
Deadline 2027-03-05FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) represents one of the earliest and most successful forms of cellular immunotherapy. However, i...
Advancing allogeneic transplantation through multi-donor, immunotherapy, and precision strategies
Deadline 2027-03-05FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) represents one of the earliest and most successful forms of cellular immunotherapy. However, i...
Community Series in Crosstalk in Ferroptosis, Immunity & Inflammation: Volume III
Deadline 2027-03-05FrontiersIndexed (Active)
Journal: Frontiers in Immunology
This Research Topic is the third volume of the “Crosstalk in Ferroptosis, Immunity & Inflammation” Community Series. Please see Volume I hereFerroptosis repr...
Community Series in Crosstalk in Ferroptosis, Immunity & Inflammation: Volume III
Deadline 2027-03-05FrontiersIndexed (Active)
Journal: Frontiers in Immunology
This Research Topic is the third volume of the “Crosstalk in Ferroptosis, Immunity & Inflammation” Community Series. Please see Volume I hereFerroptosis repr...
Ecto enzymes and purinergic signaling as immune modulation strategies in parasitic infections
Deadline 2027-03-06FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Parasitic immunology examines how protozoan and helminth parasites manipulate host immunity to establish persistent infections. Increasing evidence identifie...
Ecto enzymes and purinergic signaling as immune modulation strategies in parasitic infections
Deadline 2027-03-06FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Parasitic immunology examines how protozoan and helminth parasites manipulate host immunity to establish persistent infections. Increasing evidence identifie...
Neuro-immune crosstalk in peripheral neuropathy: from mechanisms to therapeutic opportunities: Volume II
Deadline 2027-03-06FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Peripheral neuropathy encompasses a variety of conditions marked by damage or lesions to peripheral nerves, resulting in symptoms such as pain, itch, and sen...
Neuro-immune crosstalk in peripheral neuropathy: from mechanisms to therapeutic opportunities: Volume II
Deadline 2027-03-06FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Peripheral neuropathy encompasses a variety of conditions marked by damage or lesions to peripheral nerves, resulting in symptoms such as pain, itch, and sen...
Community Series in Immune modulation at the crossroads of viral infection and tumor progression - Volume II
Deadline 2027-03-07FrontiersIndexed (Active)
Journal: Frontiers in Immunology
The interplay between viruses and tumor progression represents a critical area of study, as certain oncogenic viruses, such as HPV, EBV, and HBV, are known t...
Community Series in Immune modulation at the crossroads of viral infection and tumor progression - Volume II
Deadline 2027-03-07FrontiersIndexed (Active)
Journal: Frontiers in Immunology
The interplay between viruses and tumor progression represents a critical area of study, as certain oncogenic viruses, such as HPV, EBV, and HBV, are known t...
Vaccines and adjuvants as modulators of the inflammatory microenvironment: immune signaling beyond the vaccine response
Deadline 2027-03-07FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Vaccines and adjuvants are conventionally studied for the magnitude and specificity of the antigen-directed immune response they generate. Less attention has...
Vaccines and adjuvants as modulators of the inflammatory microenvironment: immune signaling beyond the vaccine response
Deadline 2027-03-07FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Vaccines and adjuvants are conventionally studied for the magnitude and specificity of the antigen-directed immune response they generate. Less attention has...
Neuroimmune T cell dysregulation in multiple sclerosis: epigenetic mechanisms and antigen-specific interventions
Deadline 2027-03-12FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Multiple Sclerosis (MS) is, at its core, a disease of failed molecular immune regulation. Autoreactive T cells shaped by aberrant transcriptional programs an...
Neuroimmune T cell dysregulation in multiple sclerosis: epigenetic mechanisms and antigen-specific interventions
Deadline 2027-03-12FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Multiple Sclerosis (MS) is, at its core, a disease of failed molecular immune regulation. Autoreactive T cells shaped by aberrant transcriptional programs an...
m6A modification in immune cell-regulated inflammatory diseases: Volume II
Deadline 2027-03-13FrontiersIndexed (Active)
Journal: Frontiers in Immunology
N6-methyladenosine (m6A) serves as a critical RNA modification, dynamically governing RNA metabolism through its influence on RNA stability, splicing, transl...
m6A modification in immune cell-regulated inflammatory diseases: Volume II
Deadline 2027-03-13FrontiersIndexed (Active)
Journal: Frontiers in Immunology
N6-methyladenosine (m6A) serves as a critical RNA modification, dynamically governing RNA metabolism through its influence on RNA stability, splicing, transl...
Anthropogenic Chemical Stressors and Host Defence in Wild Populations
Deadline 2027-03-15FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Anthropogenic chemical stressors, including pesticides (insecticides and fungicides), per- and polyfluoroalkyl substances (PFAS), microplastics, and other em...
Anthropogenic Chemical Stressors and Host Defence in Wild Populations
Deadline 2027-03-15FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Anthropogenic chemical stressors, including pesticides (insecticides and fungicides), per- and polyfluoroalkyl substances (PFAS), microplastics, and other em...
Community series in Advances in molecular diagnostics of allergy: novel allergens, biomarkers, and technical developments: Volume II
Deadline 2027-03-15FrontiersIndexed (Active)
Journal: Frontiers in Immunology
This Research Topic is the second volume of the “Advances in molecular diagnostics of allergy: novel allergens, biomarkers, and technical developments” Commu...
Community series in Advances in molecular diagnostics of allergy: novel allergens, biomarkers, and technical developments: Volume II
Deadline 2027-03-15FrontiersIndexed (Active)
Journal: Frontiers in Immunology
This Research Topic is the second volume of the “Advances in molecular diagnostics of allergy: novel allergens, biomarkers, and technical developments” Commu...
Immune Monitoring approaches to Clinical Studies in Immunotherapeutics, Vaccines, and Gene Therapy
Deadline 2027-03-15FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Immune monitoring is the quantitative analysis of the magnitude, breadth, and specificity of immune responses and is an essential component of pre-clinical a...
Immune Monitoring approaches to Clinical Studies in Immunotherapeutics, Vaccines, and Gene Therapy
Deadline 2027-03-15FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Immune monitoring is the quantitative analysis of the magnitude, breadth, and specificity of immune responses and is an essential component of pre-clinical a...
Checkpoint immunotherapy: Reshaping the landscape of gastrointestinal cancer treatment - Volume IV
Deadline 2027-03-16FrontiersIndexed (Active)
Journal: Frontiers in Immunology
"Checkpoint Immunotherapy: Reshaping the Landscape of Gastrointestinal Cancer Treatment" is a comprehensive Research Topic that delves into the transformativ...
Checkpoint immunotherapy: Reshaping the landscape of gastrointestinal cancer treatment - Volume IV
Deadline 2027-03-16FrontiersIndexed (Active)
Journal: Frontiers in Immunology
"Checkpoint Immunotherapy: Reshaping the Landscape of Gastrointestinal Cancer Treatment" is a comprehensive Research Topic that delves into the transformativ...
Advancing prophylaxis and management of acute graft-versus-host disease in the era of novel therapies
Deadline 2027-03-19FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Allogeneic hematopoietic cell transplantation is a cornerstone treatment for many high-risk hematological malignancies, yet acute graft-versus-host disease (...
Advancing prophylaxis and management of acute graft-versus-host disease in the era of novel therapies
Deadline 2027-03-19FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Allogeneic hematopoietic cell transplantation is a cornerstone treatment for many high-risk hematological malignancies, yet acute graft-versus-host disease (...
Dual role of humoral immunity and complement system in endometriosis
Deadline 2027-03-19FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Endometriosis (EM) is a chronic gynaecological condition affecting approximately 5-10% of women of reproductive age. It is characterized by the presence of f...
Dual role of humoral immunity and complement system in endometriosis
Deadline 2027-03-19FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Endometriosis (EM) is a chronic gynaecological condition affecting approximately 5-10% of women of reproductive age. It is characterized by the presence of f...
Innate immunity in fish: responses and adaptations to diverse aquatic environments: Volume II
Deadline 2027-03-19FrontiersIndexed (Active)
Journal: Frontiers in Immunology
The area of innate immunity in fish is a critical frontier for aquaculture, an essential industry providing significant protein sources globally. Fish innate...
Innate immunity in fish: responses and adaptations to diverse aquatic environments: Volume II
Deadline 2027-03-19FrontiersIndexed (Active)
Journal: Frontiers in Immunology
The area of innate immunity in fish is a critical frontier for aquaculture, an essential industry providing significant protein sources globally. Fish innate...
Triggers and tolerance of T cell networks in microbial immunity and autoimmune diseases
Deadline 2027-03-19FrontiersIndexed (Active)
Journal: Frontiers in Immunology
T cells sit at the junction between protective immunity and self-tolerance. Microbial exposure, whether from commensal or pathogenic organisms, shapes T cell...
Triggers and tolerance of T cell networks in microbial immunity and autoimmune diseases
Deadline 2027-03-19FrontiersIndexed (Active)
Journal: Frontiers in Immunology
T cells sit at the junction between protective immunity and self-tolerance. Microbial exposure, whether from commensal or pathogenic organisms, shapes T cell...
Vertical viral transmission and immune programming of the developing lung: from cytokine signaling to respiratory disease
Deadline 2027-03-19FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Maternal respiratory viral infections during pregnancy can cross into the fetal compartment and reshape the immune and inflammatory environment of the develo...
Vertical viral transmission and immune programming of the developing lung: from cytokine signaling to respiratory disease
Deadline 2027-03-19FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Maternal respiratory viral infections during pregnancy can cross into the fetal compartment and reshape the immune and inflammatory environment of the develo...
Cell-type-specific regulated cell deaths in the tumor immune microenvironment
Deadline 2027-03-20FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Cancer immunology and regulated cell deaths are closely connected fields that are reshaping our understanding of tumor progression and therapeutic response. ...
Cell-type-specific regulated cell deaths in the tumor immune microenvironment
Deadline 2027-03-20FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Cancer immunology and regulated cell deaths are closely connected fields that are reshaping our understanding of tumor progression and therapeutic response. ...
The Aging Brain Immune Interface: Mechanisms of Neuroinflammation, Immune Dysregulation, and Neurodegeneration
Deadline 2027-03-20FrontiersIndexed (Active)
Journal: Frontiers in Immunology
The aging brain sits at a crossroads where immune vigilance gradually gives way to chronic, low grade inflammation and impaired repair capacity. Microglia wh...
The Aging Brain Immune Interface: Mechanisms of Neuroinflammation, Immune Dysregulation, and Neurodegeneration
Deadline 2027-03-20FrontiersIndexed (Active)
Journal: Frontiers in Immunology
The aging brain sits at a crossroads where immune vigilance gradually gives way to chronic, low grade inflammation and impaired repair capacity. Microglia wh...
Immune-parenchymal ligand-receptor axes: Microenvironmental control of tissue cell phenotypes in tumor and non-tumor diseases, volume II
Deadline 2027-03-23FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Across organs and disease contexts, immune cells shape the behavior of tissue parenchymal cells through short-range and long-range cues. A central layer of t...
Immune-parenchymal ligand-receptor axes: Microenvironmental control of tissue cell phenotypes in tumor and non-tumor diseases, volume II
Deadline 2027-03-23FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Across organs and disease contexts, immune cells shape the behavior of tissue parenchymal cells through short-range and long-range cues. A central layer of t...
Mechanisms and durability of humoral and cellular immunity elicited by self-amplifying mRNA (sa-mRNA) platforms
Deadline 2027-03-23FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Self-amplifying messenger RNA (sa-mRNA) platforms represent a transformative evolution in vaccinology. By leveraging intracellular replication machinery, sa-...
Mechanisms and durability of humoral and cellular immunity elicited by self-amplifying mRNA (sa-mRNA) platforms
Deadline 2027-03-23FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Self-amplifying messenger RNA (sa-mRNA) platforms represent a transformative evolution in vaccinology. By leveraging intracellular replication machinery, sa-...
Reinvigorating NK cells and innate lymphoid cells for therapeutic immunity
Deadline 2027-03-23FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Natural killer (NK) cells and other innate lymphoid cells (ILCs) are central to immune surveillance, tissue homeostasis, and host defence, while also contrib...
Reinvigorating NK cells and innate lymphoid cells for therapeutic immunity
Deadline 2027-03-23FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Natural killer (NK) cells and other innate lymphoid cells (ILCs) are central to immune surveillance, tissue homeostasis, and host defence, while also contrib...
Host–Virus Interactions and Innate/Adaptive Immune Responses in Bovine Viral Diseases
Deadline 2027-03-27FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Viral diseases remain among the most significant threats to cattle health, productivity, and food security worldwide, causing substantial economic losses in ...
Gut dysbiosis and the gut-liver-brain axis in neuroimmune pathology
Deadline 2027-03-28FrontiersIndexed (Active)
Journal: Frontiers in Immunology
The intestinal mucosal barrier is a critical checkpoint between the gut microbiota and the host immune system. When barrier integrity fails, whether through ...
Gut dysbiosis and the gut-liver-brain axis in neuroimmune pathology
Deadline 2027-03-28FrontiersIndexed (Active)
Journal: Frontiers in Immunology
The intestinal mucosal barrier is a critical checkpoint between the gut microbiota and the host immune system. When barrier integrity fails, whether through ...
Complement & pentraxin immunity: mechanisms, disease pathogenesis, and therapeutic opportunities
Deadline 2027-03-29FrontiersIndexed (Active)
Journal: Frontiers in Immunology
The complement system is a cornerstone of innate immunity - an evolutionarily ancient yet remarkably versatile effector network that eliminates pathogens, cl...
Complement & pentraxin immunity: mechanisms, disease pathogenesis, and therapeutic opportunities
Deadline 2027-03-29FrontiersIndexed (Active)
Journal: Frontiers in Immunology
The complement system is a cornerstone of innate immunity - an evolutionarily ancient yet remarkably versatile effector network that eliminates pathogens, cl...
Increased risk of mycobacterial infections in autoimmune diseases
Deadline 2027-03-29FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Patients with autoimmune diseases are at significantly increased risk of infections caused by Mycobacterium Tuberculosis (TB) and Nontuberculous Mycobacteria...
Increased risk of mycobacterial infections in autoimmune diseases
Deadline 2027-03-29FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Patients with autoimmune diseases are at significantly increased risk of infections caused by Mycobacterium Tuberculosis (TB) and Nontuberculous Mycobacteria...
Islet–Immune Cell Communication in Diabetes: Mechanisms, Extracellular Vesicles, and Therapeutic Opportunities
Deadline 2027-03-29FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Type 1 (autoimmune) and Type 2 (metabolic) diabetes both arise from progressive failure of pancreatic islet cells, but the immune system plays a central and ...
Crosstalk between immune regulation, epigenetic reprogramming, and genomic instability in cancer development and therapy
Deadline 2027-03-31FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Cancer arises and progresses through a tight interplay between immune surveillance, epigenetic reprogramming, and genomic instability. These three layers do ...
Crosstalk between immune regulation, epigenetic reprogramming, and genomic instability in cancer development and therapy
Deadline 2027-03-31FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Cancer arises and progresses through a tight interplay between immune surveillance, epigenetic reprogramming, and genomic instability. These three layers do ...
Decoding adaptive immune states and trajectories in cancer with immune twins
Deadline 2027-03-31FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Immunity has long stood as a correlate of health. The immune system is traditionally understood as a central guardian, prepared to protect against infections...
Decoding adaptive immune states and trajectories in cancer with immune twins
Deadline 2027-03-31FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Immunity has long stood as a correlate of health. The immune system is traditionally understood as a central guardian, prepared to protect against infections...
Predictive biomarkers for treatment response in inflammatory arthritis: advancing precision medicine
Deadline 2027-03-31FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Inflammatory arthritis encompasses a heterogeneous group of immune-mediated conditions, including rheumatoid arthritis, psoriatic arthritis, axial spondyloar...
Predictive biomarkers for treatment response in inflammatory arthritis: advancing precision medicine
Deadline 2027-03-31FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Inflammatory arthritis encompasses a heterogeneous group of immune-mediated conditions, including rheumatoid arthritis, psoriatic arthritis, axial spondyloar...
B cells and innate immune cells: roles in cancer, autoimmune disorders, and therapeutic interventions
Deadline 2027-04-30FrontiersIndexed (Active)
Journal: Frontiers in Immunology
B cells and innate immune cells, like natural killer cells, macrophages, and neutrophils, have shown important contributions to the progression and control o...
B cells and innate immune cells: roles in cancer, autoimmune disorders, and therapeutic interventions
Deadline 2027-04-30FrontiersIndexed (Active)
Journal: Frontiers in Immunology
B cells and innate immune cells, like natural killer cells, macrophages, and neutrophils, have shown important contributions to the progression and control o...
Behçet’s Syndrome: from pathophysiology to personalized therapeutics - Volume II
Deadline 2027-04-30FrontiersIndexed (Active)
Journal: Frontiers in Immunology
This is the second volume of 'Behçet’s Syndrome: from pathophysiology to personalized therapeutics'. Please see volume I here.Behçet’s syndrome (BS) is a ch...
The role of Vitamin D as an immunomodulator - volume IV
Deadline 2027-04-30FrontiersIndexed (Active)
Journal: Frontiers in Immunology
This Research Topic is the fourth volume of "The Role of Vitamin D as an Immunomodulator". Please see volume I here II here & III here.Vitamin D, a compound ...
The role of Vitamin D as an immunomodulator - volume IV
Deadline 2027-04-30FrontiersIndexed (Active)
Journal: Frontiers in Immunology
This Research Topic is the fourth volume of "The Role of Vitamin D as an Immunomodulator". Please see volume I here II here & III here.Vitamin D, a compound ...
Environmental triggers and epigenetics involved in autoimmune and autoinflammatory disorders - volume II
Deadline 2027-05-21FrontiersIndexed (Active)
Journal: Frontiers in Immunology
This Research Topic is the second volume in this series, "Environmental triggers and epigenetics, involved in autoimmune and autoinflammatory disorders". Ple...
Environmental triggers and epigenetics involved in autoimmune and autoinflammatory disorders - volume II
Deadline 2027-05-21FrontiersIndexed (Active)
Journal: Frontiers in Immunology
This Research Topic is the second volume in this series, "Environmental triggers and epigenetics, involved in autoimmune and autoinflammatory disorders". Ple...
Enhancing DNA vaccine efficacy with engineered nanoparticles in cancer immunotherapy
Deadline 2027-06-23FrontiersIndexed (Active)
Journal: Frontiers in Immunology
DNA vaccines hold promise for cancer immunotherapy due to their safety and rapid design capabilities. However, their clinical application is hindered by chal...
Enhancing DNA vaccine efficacy with engineered nanoparticles in cancer immunotherapy
Deadline 2027-06-23FrontiersIndexed (Active)
Journal: Frontiers in Immunology
DNA vaccines hold promise for cancer immunotherapy due to their safety and rapid design capabilities. However, their clinical application is hindered by chal...
Community Series in enhancing T Cell function: Innovations in cancer immunotherapy, Volume III
Deadline 2027-06-26FrontiersIndexed (Active)
Journal: Frontiers in Immunology
This Research Topic is the second volume of the “Immune Responses Against Tumors - From the Bench to the Bedside” Community Series. Please see Volume I here ...
Community Series in enhancing T Cell function: Innovations in cancer immunotherapy, Volume III
Deadline 2027-06-26FrontiersIndexed (Active)
Journal: Frontiers in Immunology
This Research Topic is the second volume of the “Immune Responses Against Tumors - From the Bench to the Bedside” Community Series. Please see Volume I here ...
Community series in precision immuno-oncology: harnessing novel drug development, biomarkers, and nanoparticle-based therapeutic platforms to overcome cancer resistance: volume II
Deadline 2027-06-26FrontiersIndexed (Active)
Journal: Frontiers in Immunology
This Research Topic is the second volume of the “Precision Immuno-Oncology: Harnessing Novel Drug Development, Biomarkers, and Nanoparticle-Based Therapeutic...
Community series in precision immuno-oncology: harnessing novel drug development, biomarkers, and nanoparticle-based therapeutic platforms to overcome cancer resistance: volume II
Deadline 2027-06-26FrontiersIndexed (Active)
Journal: Frontiers in Immunology
This Research Topic is the second volume of the “Precision Immuno-Oncology: Harnessing Novel Drug Development, Biomarkers, and Nanoparticle-Based Therapeutic...
Precision alloimmunity: immunogenetics, antibody-mediated mechanisms, and translational strategies in transfusion and transplantation
Deadline 2027-06-30FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Alloimmunity remains a formidable challenge in the domains of organ and hematopoietic stem cell transplantation, as well as transfusion medicine. The intrica...
Precision alloimmunity: immunogenetics, antibody-mediated mechanisms, and translational strategies in transfusion and transplantation
Deadline 2027-06-30FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Alloimmunity remains a formidable challenge in the domains of organ and hematopoietic stem cell transplantation, as well as transfusion medicine. The intrica...
Real-world evidence across diverse malignancies: Integrating immunotherapy efficacy, toxicity profiles, and predictive biomarkers
Deadline 2027-06-30FrontiersIndexed (Active)
Journal: Frontiers in Immunology
While immunotherapy has fundamentally transformed the clinical management of genitourinary (GU) and gastrointestinal (GI) malignancies, two critical mechanis...
Real-world evidence across diverse malignancies: Integrating immunotherapy efficacy, toxicity profiles, and predictive biomarkers
Deadline 2027-06-30FrontiersIndexed (Active)
Journal: Frontiers in Immunology
While immunotherapy has fundamentally transformed the clinical management of genitourinary (GU) and gastrointestinal (GI) malignancies, two critical mechanis...
Intrinsic and innate antiviral immunity against emerging viral infections: restriction factors, sensing pathways, and virus–host coevolution
Deadline 2027-07-01FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Emerging viral infections continue to pose major challenges to global human and animal health, as highlighted by recent Mpox outbreaks, the COVID-19 pandemic...
Identifying common ground: immune modulating therapeutics with applications across solid organ transplant and gene therapy
Deadline 2027-07-02FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Immune modulating therapeutics have applications across solid organ transplant and gene therapy. Immune suppression therapeutics (e.g. calcineurin inhibitors...
Identifying common ground: immune modulating therapeutics with applications across solid organ transplant and gene therapy
Deadline 2027-07-02FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Immune modulating therapeutics have applications across solid organ transplant and gene therapy. Immune suppression therapeutics (e.g. calcineurin inhibitors...
Small molecule immunomodulator or immunotherapy potentiators in cancer therapy
Deadline 2027-07-07FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Immunotherapy for cancer treatment has seen unprecedented advancements in recent years. However, all current immunotherapies are based on biological molecule...
Small molecule immunomodulator or immunotherapy potentiators in cancer therapy
Deadline 2027-07-07FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Immunotherapy for cancer treatment has seen unprecedented advancements in recent years. However, all current immunotherapies are based on biological molecule...
Advanced hepatocellular carcinoma in the immunotherapy era: real-world immune dynamics and multidisciplinary strategies beyond clinical trials
Deadline 2027-07-11FrontiersIndexed (Active)
Journal: Frontiers in Immunology
The immunotherapy revolution has fundamentally altered the treatment landscape of advanced hepatocellular carcinoma (HCC), yet the immune biology underlying ...
Advanced hepatocellular carcinoma in the immunotherapy era: real-world immune dynamics and multidisciplinary strategies beyond clinical trials
Deadline 2027-07-11FrontiersIndexed (Active)
Journal: Frontiers in Immunology
The immunotherapy revolution has fundamentally altered the treatment landscape of advanced hepatocellular carcinoma (HCC), yet the immune biology underlying ...
Cancer-associated fibroblast heterogeneity and its role in shaping tumor immunosuppression
Deadline 2027-07-13FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Cancer-associated fibroblasts (CAFs) are a dominant and functionally diverse component of the tumor stroma, long recognized for promoting tumor growth, invas...
Cancer-associated fibroblast heterogeneity and its role in shaping tumor immunosuppression
Deadline 2027-07-13FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Cancer-associated fibroblasts (CAFs) are a dominant and functionally diverse component of the tumor stroma, long recognized for promoting tumor growth, invas...
Immune dysregulation and signaling pathways in cancer progression, immune escape, and therapy response
Deadline 2027-07-16FrontiersIndexed (Active)
Journal: Frontiers in Immunology
The tumor microenvironment (TME) is a complex and evolving ecosystem that plays a critical role in immune evasion, cancer development and progression. It con...
Immune dysregulation and signaling pathways in cancer progression, immune escape, and therapy response
Deadline 2027-07-16FrontiersIndexed (Active)
Journal: Frontiers in Immunology
The tumor microenvironment (TME) is a complex and evolving ecosystem that plays a critical role in immune evasion, cancer development and progression. It con...
Immunological Mechanisms of Sex Differences in Infectious Disease Outcomes and Vaccine Responses
Deadline 2027-07-17FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Biological sex is a critical determinant of susceptibility, disease progression, and treatment outcomes in infectious diseases, driven primarily by fundament...
Immunological Mechanisms of Sex Differences in Infectious Disease Outcomes and Vaccine Responses
Deadline 2027-07-17FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Biological sex is a critical determinant of susceptibility, disease progression, and treatment outcomes in infectious diseases, driven primarily by fundament...
Microbial Secretion Systems and Host Immune Responses: From Symbiosis to Pathogenesis
Deadline 2027-07-19FrontiersIndexed (Active)
Journal: Frontiers in Immunology
The vertebrate immune system has co-evolved alongside an extraordinary diversity of microorganisms, many of which deploy specialised secretion machineries to...
Microbial Secretion Systems and Host Immune Responses: From Symbiosis to Pathogenesis
Deadline 2027-07-19FrontiersIndexed (Active)
Journal: Frontiers in Immunology
The vertebrate immune system has co-evolved alongside an extraordinary diversity of microorganisms, many of which deploy specialised secretion machineries to...
Cellular Immunotherapies: From Basic Insights to Novel Clinical Applications
Deadline 2027-07-20FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Cellular immunotherapy has transformed modern medicine by harnessing and reprogramming immune cells to combat serious diseases. While T cell-based approaches...
Cellular Immunotherapies: From Basic Insights to Novel Clinical Applications
Deadline 2027-07-20FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Cellular immunotherapy has transformed modern medicine by harnessing and reprogramming immune cells to combat serious diseases. While T cell-based approaches...
Molecular immunopathogenesis and immunotherapy research in hepatitis B virus infection
Deadline 2027-07-20FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Hepatitis B is a virus-triggered but host’s immune system-mediated liver disease frequently advancing to chronic hepatitis B (CHB) and primary hepatocellular...
Molecular immunopathogenesis and immunotherapy research in hepatitis B virus infection
Deadline 2027-07-20FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Hepatitis B is a virus-triggered but host’s immune system-mediated liver disease frequently advancing to chronic hepatitis B (CHB) and primary hepatocellular...
Comparative and translational immunology of immune-mediated diseases in companion animals
Deadline 2027-07-21FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Companion animals, including dogs, cats, horses, and other domesticated species, develop a wide range of naturally occurring immune-mediated, inflammatory, a...
Comparative and translational immunology of immune-mediated diseases in companion animals
Deadline 2027-07-21FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Companion animals, including dogs, cats, horses, and other domesticated species, develop a wide range of naturally occurring immune-mediated, inflammatory, a...
Blending pathology and immunology - New frontiers: Volume II
Deadline 2027-07-31FrontiersIndexed (Active)
Journal: Frontiers in Immunology
This Research Topic is the second volume of the series on the "Blending Pathology and Immunology - New Frontiers". Please see the first volume of this collec...
Blending pathology and immunology - New frontiers: Volume II
Deadline 2027-07-31FrontiersIndexed (Active)
Journal: Frontiers in Immunology
This Research Topic is the second volume of the series on the "Blending Pathology and Immunology - New Frontiers". Please see the first volume of this collec...
Immune-metabolic crosstalk in type 2 diabetes and its target-organ complications: The liver, pancreatic islet, and beyond
Deadline 2027-07-31FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Type 2 diabetes (T2D) is increasingly understood as a disease of disrupted immune-metabolic crosstalk rather than metabolic dysfunction alone. Chronic low-gr...
Immune-metabolic crosstalk in type 2 diabetes and its target-organ complications: The liver, pancreatic islet, and beyond
Deadline 2027-07-31FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Type 2 diabetes (T2D) is increasingly understood as a disease of disrupted immune-metabolic crosstalk rather than metabolic dysfunction alone. Chronic low-gr...
Stem cell transplantation in the era of post-transplant cyclophosphamide (PTCy): Donor biology, immunosenescence, and transplant immunology
Deadline 2027-07-31FrontiersIndexed (Active)
Journal: Frontiers in Immunology
The field of allogeneic hematopoietic stem cell transplantation (HSCT) has been significantly transformed by the use of post-transplant cyclophosphamide (PTC...
Stem cell transplantation in the era of post-transplant cyclophosphamide (PTCy): Donor biology, immunosenescence, and transplant immunology
Deadline 2027-07-31FrontiersIndexed (Active)
Journal: Frontiers in Immunology
The field of allogeneic hematopoietic stem cell transplantation (HSCT) has been significantly transformed by the use of post-transplant cyclophosphamide (PTC...
Immunological complexity of lupus across diverse populations: Pathogenesis, biomarkers, and translational gaps
Deadline 2027-08-01FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Systemic lupus erythematosus (SLE) is an archetypal autoimmune disorder characterized by disrupted immune tolerance, abnormal type I interferon signaling, dy...
Immunological complexity of lupus across diverse populations: Pathogenesis, biomarkers, and translational gaps
Deadline 2027-08-01FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Systemic lupus erythematosus (SLE) is an archetypal autoimmune disorder characterized by disrupted immune tolerance, abnormal type I interferon signaling, dy...
Immunometabolism of T cell function in infection, cancer, and vaccination
Deadline 2027-08-01FrontiersIndexed (Active)
Journal: Frontiers in Immunology
T cells represent a cornerstone of adaptive immunity, and recent advances in immunometabolism have revealed that metabolic circuits are not merely passive en...
Immunometabolism of T cell function in infection, cancer, and vaccination
Deadline 2027-08-01FrontiersIndexed (Active)
Journal: Frontiers in Immunology
T cells represent a cornerstone of adaptive immunity, and recent advances in immunometabolism have revealed that metabolic circuits are not merely passive en...
Molecular determinants of treatment response and patient stratification in rheumatoid arthritis
Deadline 2027-08-01FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Rheumatoid arthritis (RA) remains one of the most clinically heterogeneous autoimmune conditions, with treatment outcomes varying dramatically across patient...
Molecular determinants of treatment response and patient stratification in rheumatoid arthritis
Deadline 2027-08-01FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Rheumatoid arthritis (RA) remains one of the most clinically heterogeneous autoimmune conditions, with treatment outcomes varying dramatically across patient...
Mechanisms of immune resistance in the colorectal cancer tumor microenvironment: Insights from preclinical mouse models and emerging therapeutic strategies
Deadline 2027-08-11FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Colorectal cancer (CRC) remains a leading cause of cancer-related mortality worldwide, with disease progression and treatment outcome tightly coupled to the ...
Mechanisms of immune resistance in the colorectal cancer tumor microenvironment: Insights from preclinical mouse models and emerging therapeutic strategies
Deadline 2027-08-11FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Colorectal cancer (CRC) remains a leading cause of cancer-related mortality worldwide, with disease progression and treatment outcome tightly coupled to the ...
Precision nutritional immunology: Personalized dietary strategies for immune disorders
Deadline 2027-08-14FrontiersIndexed (Active)
Journal: Frontiers in Immunology
The relationship between diet and immunity is neither simple nor uniform. What we eat shapes how our immune system develops, responds to threats, and recover...
Precision nutritional immunology: Personalized dietary strategies for immune disorders
Deadline 2027-08-14FrontiersIndexed (Active)
Journal: Frontiers in Immunology
The relationship between diet and immunity is neither simple nor uniform. What we eat shapes how our immune system develops, responds to threats, and recover...
Next-generation immune-engaging therapies in small cell lung cancer: Biology, translation and resistance
Deadline 2027-08-16FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Small cell lung cancer (SCLC) is an aggressive neuroendocrine malignancy characterized by rapid progression, early dissemination, and limited durability of c...
Next-generation immune-engaging therapies in small cell lung cancer: Biology, translation and resistance
Deadline 2027-08-16FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Small cell lung cancer (SCLC) is an aggressive neuroendocrine malignancy characterized by rapid progression, early dissemination, and limited durability of c...
Mucosal defense mechanisms against bacterial respiratory infections
Deadline 2027-08-17FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Bacterial respiratory infections are among the leading causes of morbidity and mortality worldwide. Pathogens such as Streptococcus pneumoniae, Staphylococcu...
Mucosal defense mechanisms against bacterial respiratory infections
Deadline 2027-08-17FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Bacterial respiratory infections are among the leading causes of morbidity and mortality worldwide. Pathogens such as Streptococcus pneumoniae, Staphylococcu...
Neuroimmune and metabolic regulation of the tumor microenvironment in immunotherapy
Deadline 2027-08-24FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Recent advances in cancer immunology have established the tumor microenvironment (TME) as a dynamic regulator of therapeutic response. Metabolic competition,...
Neuroimmune and metabolic regulation of the tumor microenvironment in immunotherapy
Deadline 2027-08-24FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Recent advances in cancer immunology have established the tumor microenvironment (TME) as a dynamic regulator of therapeutic response. Metabolic competition,...
HIV-associated comorbidities in the ART era: clinical challenges and translational perspectives
Deadline 2027-08-31FrontiersIndexed (Active)
Journal: Frontiers in Immunology
The widespread use of effective antiretroviral therapy (ART) has transformed HIV infection into a chronic condition, significantly improving life expectancy ...
HIV-associated comorbidities in the ART era: clinical challenges and translational perspectives
Deadline 2027-08-31FrontiersIndexed (Active)
Journal: Frontiers in Immunology
The widespread use of effective antiretroviral therapy (ART) has transformed HIV infection into a chronic condition, significantly improving life expectancy ...
Immunity, inflammation, tissue recovery, and intervention strategies against acute respiratory virus infection
Deadline 2027-08-31FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Acute respiratory viral infections, including influenza, COVID-19, and respiratory syncytial virus (RSV), remain major causes of morbidity and mortality worl...
Immunity, inflammation, tissue recovery, and intervention strategies against acute respiratory virus infection
Deadline 2027-08-31FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Acute respiratory viral infections, including influenza, COVID-19, and respiratory syncytial virus (RSV), remain major causes of morbidity and mortality worl...
Natural products modulating antiviral immune responses and infection-induced neuroinflammation
Deadline 2027-08-31FrontiersIndexed (Active)
Journal: Frontiers in Immunology
The interface between antiviral immune responses and neuroinflammation is increasingly recognized as an important determinant of disease severity and recover...
Natural products modulating antiviral immune responses and infection-induced neuroinflammation
Deadline 2027-08-31FrontiersIndexed (Active)
Journal: Frontiers in Immunology
The interface between antiviral immune responses and neuroinflammation is increasingly recognized as an important determinant of disease severity and recover...
Immune digital twins: modeling disease trajectories and therapeutic response
Deadline 2027-09-03FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Immune responses are highly dynamic, context-dependent processes shaped by antigen exposure, tissue microenvironment, cross-talk between innate and adaptive ...
Immune digital twins: modeling disease trajectories and therapeutic response
Deadline 2027-09-03FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Immune responses are highly dynamic, context-dependent processes shaped by antigen exposure, tissue microenvironment, cross-talk between innate and adaptive ...
Microbial and metabolic remodeling of the tumor microenvironment in solid cancer immunotherapy resistance
Deadline 2027-09-06FrontiersIndexed (Active)
Journal: Frontiers in Immunology
The tumor microenvironment (TME) comprises diverse cellular and non-cellular components, including stromal cells, fibroblasts, endothelial cells, lymphocytes...
Microbial and metabolic remodeling of the tumor microenvironment in solid cancer immunotherapy resistance
Deadline 2027-09-06FrontiersIndexed (Active)
Journal: Frontiers in Immunology
The tumor microenvironment (TME) comprises diverse cellular and non-cellular components, including stromal cells, fibroblasts, endothelial cells, lymphocytes...
Perioperative immunotherapy and immune surveillance in hepatocellular carcinoma
Deadline 2027-09-06FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Hepatocellular carcinoma (HCC) continues to carry a substantial risk of recurrence after potentially curative liver resection. The perioperative period repre...
Perioperative immunotherapy and immune surveillance in hepatocellular carcinoma
Deadline 2027-09-06FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Hepatocellular carcinoma (HCC) continues to carry a substantial risk of recurrence after potentially curative liver resection. The perioperative period repre...
Artificial intelligence-enabled integrative medicine for chronic inflammatory diseases
Deadline 2027-09-07FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Chronic inflammatory diseases are characterized by persistent immune activation, tissue remodeling, oxidative stress, fibrosis, and progressive organ dysfunc...
Artificial intelligence-enabled integrative medicine for chronic inflammatory diseases
Deadline 2027-09-07FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Chronic inflammatory diseases are characterized by persistent immune activation, tissue remodeling, oxidative stress, fibrosis, and progressive organ dysfunc...
Metabolic reprogramming as the next frontier in cell therapy and cancer immunotherapy for solid tumors
Deadline 2027-09-08FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Cell-based immunotherapies offer a promising alternative for treating certain hematological malignancies. The therapeutic landscape has expanded to include c...
Metabolic reprogramming as the next frontier in cell therapy and cancer immunotherapy for solid tumors
Deadline 2027-09-08FrontiersIndexed (Active)
Journal: Frontiers in Immunology
Cell-based immunotherapies offer a promising alternative for treating certain hematological malignancies. The therapeutic landscape has expanded to include c...
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