Migrastatic Agents, Metastasis, and Mitochondrial Metabolism: Emerging Strategies for Cancer Drug Discovery
Deadline 2027-02-28FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Cancer remains one of the leading causes of death worldwide. Despite substantial progress in developing effective therapies over the past century, it remains...
Migrastatic Agents, Metastasis, and Mitochondrial Metabolism: Emerging Strategies for Cancer Drug Discovery
Deadline 2027-02-28FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Cancer remains one of the leading causes of death worldwide. Despite substantial progress in developing effective therapies over the past century, it remains...
Molecular basis of chemosensitivity
Deadline 2027-03-07FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Chemosensitivity — the degree to which cancer cells respond to therapeutic agents — remains one of the central determinants of treatment success in oncology....
Molecular basis of chemosensitivity
Deadline 2027-03-07FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Chemosensitivity — the degree to which cancer cells respond to therapeutic agents — remains one of the central determinants of treatment success in oncology....
Advances in Personalized Management of Patients with Airways Diseases
Deadline 2027-03-09FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Asthma and COPD remain leading causes of morbidity worldwide, and both are increasingly recognized as heterogeneous conditions encompassing multiple inflamma...
Advances in Personalized Management of Patients with Airways Diseases
Deadline 2027-03-09FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Asthma and COPD remain leading causes of morbidity worldwide, and both are increasingly recognized as heterogeneous conditions encompassing multiple inflamma...
Antimicrobial and Antiparasitic Drug Discovery: Experimental Pharmacology, Computational and AI/ML Approaches, and Translational Strategies
Deadline 2027-03-12FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Antimicrobial resistance is one of the defining health threats of our time. Drug-resistant bacteria, fungi, and parasites now undermine treatments that once ...
Computational Pharmacogenomics: Artificial Intelligence and Machine Learning for Variant Effect Prediction and Clinical Translation
Deadline 2027-03-12FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Over the past two decades, pharmacogenomics has shifted from common, coding variants in single populations toward genome-wide, cross-population analyses that...
Computational Pharmacogenomics: Artificial Intelligence and Machine Learning for Variant Effect Prediction and Clinical Translation
Deadline 2027-03-12FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Over the past two decades, pharmacogenomics has shifted from common, coding variants in single populations toward genome-wide, cross-population analyses that...
Fragment-Based Drug Discovery: Innovations, Challenges, and Translational Opportunities in Experimental Pharmacology
Deadline 2027-03-12FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Fragment-based drug discovery (FBDD) has rapidly evolved into a powerful approach for identifying and optimizing novel therapeutic agents. By using small, lo...
Fragment-Based Drug Discovery: Innovations, Challenges, and Translational Opportunities in Experimental Pharmacology
Deadline 2027-03-12FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Fragment-based drug discovery (FBDD) has rapidly evolved into a powerful approach for identifying and optimizing novel therapeutic agents. By using small, lo...
Institutional Implementation of Pharmacogenomics: Health Systems Policies, Barriers, and Best Practice Models
Deadline 2027-03-12FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Pharmacogenomics (PGx) offers a clinically actionable route to precision prescribing: by tailoring drug selection and dosing to an individual’s genetic profi...
Institutional Implementation of Pharmacogenomics: Health Systems Policies, Barriers, and Best Practice Models
Deadline 2027-03-12FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Pharmacogenomics (PGx) offers a clinically actionable route to precision prescribing: by tailoring drug selection and dosing to an individual’s genetic profi...
Pharmacogenomic Variability in Drug Metabolism: From Nuclear Receptors to Clinical Enzyme Regulation
Deadline 2027-03-12FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
The regulation of drug-metabolizing enzymes (DMEs) is governed by nuclear receptors (NRs) — including PXR, CAR, AhR, FXR, and PPARα — that sense xenobiotic a...
Pharmacogenomic Variability in Drug Metabolism: From Nuclear Receptors to Clinical Enzyme Regulation
Deadline 2027-03-12FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
The regulation of drug-metabolizing enzymes (DMEs) is governed by nuclear receptors (NRs) — including PXR, CAR, AhR, FXR, and PPARα — that sense xenobiotic a...
Protein Structure, Dynamics, and Function in Modern Drug Discovery
Deadline 2027-03-12FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Understanding how proteins fold, move, and interact with ligands sits at the heart of rational drug discovery. Advances in structural biology, including cryo...
Protein Structure, Dynamics, and Function in Modern Drug Discovery
Deadline 2027-03-12FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Understanding how proteins fold, move, and interact with ligands sits at the heart of rational drug discovery. Advances in structural biology, including cryo...
Real-World Safety Outcomes and Policy Responses to Adverse Drug Reactions
Deadline 2027-03-12FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Adverse drug reactions (ADRs) remain a major, and often preventable, source of patient harm even after drugs have received marketing authorization. In line w...
Real-World Safety Outcomes and Policy Responses to Adverse Drug Reactions
Deadline 2027-03-12FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Adverse drug reactions (ADRs) remain a major, and often preventable, source of patient harm even after drugs have received marketing authorization. In line w...
Artificial Intelligence in Drug Metabolism and Transport: From Multi-Omics Insights to Clinical and Pharmacological Validation
Deadline 2027-03-13FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Artificial intelligence (AI) is transforming pharmaceutical research by enabling the integration and interpretation of increasingly complex biological and ph...
Artificial Intelligence in Drug Metabolism and Transport: From Multi-Omics Insights to Clinical and Pharmacological Validation
Deadline 2027-03-13FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Artificial intelligence (AI) is transforming pharmaceutical research by enabling the integration and interpretation of increasingly complex biological and ph...
Nanoformulation Strategies to Overcome Multi-Drug Resistance in Cancer: From Pharmacological Characterization to Preclinical Translation
Deadline 2027-03-13FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Multi-drug resistance (MDR) remains the most formidable pharmacological barrier to effective cancer chemotherapy, accounting for treatment failure in the maj...
Nanoformulation Strategies to Overcome Multi-Drug Resistance in Cancer: From Pharmacological Characterization to Preclinical Translation
Deadline 2027-03-13FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Multi-drug resistance (MDR) remains the most formidable pharmacological barrier to effective cancer chemotherapy, accounting for treatment failure in the maj...
Volume II: Integrated PK/PD and Drug Metabolism Approaches in Drug Development and Evaluation
Deadline 2027-03-13FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Building on the success of Integrated PK/PD and Drug Metabolism Approaches in Drug Development and Evaluation, this Volume II continues to explore the essent...
Immunogenic Cell Death: From Mechanistic Insights to Pharmacological Intervention and Drug Discovery
Deadline 2027-03-14FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Immunogenic cell death (ICD) is a form of regulated cell death that not only eliminates stressed, damaged, or malignant cells but also actively alerts and en...
Immunogenic Cell Death: From Mechanistic Insights to Pharmacological Intervention and Drug Discovery
Deadline 2027-03-14FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Immunogenic cell death (ICD) is a form of regulated cell death that not only eliminates stressed, damaged, or malignant cells but also actively alerts and en...
Emerging Horizons of Metformin: Exploring Recent Advances and Addressing Challenges in Research and Clinical Utilization, Volume II
Deadline 2027-03-15FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Metformin remains one of the most widely prescribed oral biguanides for type 2 diabetes, yet its reach now extends far beyond glucose control. Research conti...
Emerging Horizons of Metformin: Exploring Recent Advances and Addressing Challenges in Research and Clinical Utilization, Volume II
Deadline 2027-03-15FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Metformin remains one of the most widely prescribed oral biguanides for type 2 diabetes, yet its reach now extends far beyond glucose control. Research conti...
Targeting Metabolic Reprogramming in Cancer: From Multi-Omics Signatures to Functional Pharmacology
Deadline 2027-03-16FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Cancer cells undergo extensive metabolic reprogramming to sustain proliferation, survival, invasion, and resistance to therapy. Beyond aerobic glycolysis, tu...
Targeting Metabolic Reprogramming in Cancer: From Multi-Omics Signatures to Functional Pharmacology
Deadline 2027-03-16FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Cancer cells undergo extensive metabolic reprogramming to sustain proliferation, survival, invasion, and resistance to therapy. Beyond aerobic glycolysis, tu...
Physicochemical and In Silico ADME Profiling of Gut Microbiota-Derived Metabolites: Bridging Computational Prediction and Experimental Validation
Deadline 2027-03-20FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
The gut microbiota generates hundreds of structurally distinct bioactive metabolites whose physicochemical properties govern how they behave once they reach ...
Physicochemical and In Silico ADME Profiling of Gut Microbiota-Derived Metabolites: Bridging Computational Prediction and Experimental Validation
Deadline 2027-03-20FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
The gut microbiota generates hundreds of structurally distinct bioactive metabolites whose physicochemical properties govern how they behave once they reach ...
Real-World Economic Evaluation of Advanced Therapy Medicinal Products After Market Access
Deadline 2027-03-22FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Advanced Therapy Medicinal Products (ATMPs), including gene therapies, cell-based therapies and tissue-engineered products, are transforming the therapeutic ...
Real-World Economic Evaluation of Advanced Therapy Medicinal Products After Market Access
Deadline 2027-03-22FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Advanced Therapy Medicinal Products (ATMPs), including gene therapies, cell-based therapies and tissue-engineered products, are transforming the therapeutic ...
Quantum Chemistry-Guided Design of Nitrogen-Containing Heterocycles as Anticancer Agents: From Reactivity Descriptors to Biological Validation
Deadline 2027-03-26FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Nitrogen-containing heterocycles, including pyrazoles, pyrimidines, isoxazoles, thiazoles, and naphthyridines, constitute the dominant structural class among...
Quantum Chemistry-Guided Design of Nitrogen-Containing Heterocycles as Anticancer Agents: From Reactivity Descriptors to Biological Validation
Deadline 2027-03-26FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Nitrogen-containing heterocycles, including pyrazoles, pyrimidines, isoxazoles, thiazoles, and naphthyridines, constitute the dominant structural class among...
Engineering Extracellular Communication: Glycan Interfaces, Extracellular Vesicles and Soluble Mediators for Integrative and Regenerative Pharmacology
Deadline 2027-04-15FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
The secretome is more and more recognized as a dynamic communication system regulating tissue homeostasis, immune responses and regeneration. It comprises tw...
Engineering Extracellular Communication: Glycan Interfaces, Extracellular Vesicles and Soluble Mediators for Integrative and Regenerative Pharmacology
Deadline 2027-04-15FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
The secretome is more and more recognized as a dynamic communication system regulating tissue homeostasis, immune responses and regeneration. It comprises tw...
Integrating Artificial Intelligence, Multi-Omics, and Nanomedicine to Target the Disease Immune Microenvironment
Deadline 2027-04-19FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
The immune microenvironment plays a critical role in the progression and therapeutic resistance of a broad spectrum of diseases, most notably in cancers (suc...
Integrating Artificial Intelligence, Multi-Omics, and Nanomedicine to Target the Disease Immune Microenvironment
Deadline 2027-04-19FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
The immune microenvironment plays a critical role in the progression and therapeutic resistance of a broad spectrum of diseases, most notably in cancers (suc...
Targeting Anion Channels and Associated Epithelial Ion Channels in Health and Disease: TMEM16/Anoctamins, ENaC, VRAC, and Beyond
Deadline 2027-04-26FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
The TMEM16/anoctamin family, including ANO1, ANO2, ANO6, and ANO10, is increasingly recognized as a pharmacologically tractable class of proteins with calciu...
Structure-Dependent Toxicological Profiles of PFAS: Mechanistic Determinants, Predictive Models, and Organ-Specific Biomarkers
Deadline 2027-04-30FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Per- and polyfluoroalkyl substances (PFAS) comprise a structurally diverse class of thousands of compounds, sharing a persistent carbon-fluorine backbone but...
Structure-Dependent Toxicological Profiles of PFAS: Mechanistic Determinants, Predictive Models, and Organ-Specific Biomarkers
Deadline 2027-04-30FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Per- and polyfluoroalkyl substances (PFAS) comprise a structurally diverse class of thousands of compounds, sharing a persistent carbon-fluorine backbone but...
Targeting Neuroinflammation in Spinal Cord Injury: From Inflammatory Mechanisms to Pharmacological Interventions
Deadline 2027-04-30FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Spinal cord injury (SCI) triggers a devastating secondary neuroinflammatory cascade—driven by microglial activation, immune infiltration, and sustained pro-i...
Targeting Neuroinflammation in Spinal Cord Injury: From Inflammatory Mechanisms to Pharmacological Interventions
Deadline 2027-04-30FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Spinal cord injury (SCI) triggers a devastating secondary neuroinflammatory cascade—driven by microglial activation, immune infiltration, and sustained pro-i...
One Health Biotechnology Approaches to Infectious Disease Pharmacology: Emerging Bioactive Agents for Antimicrobial and Vector-Borne Disease Control
Deadline 2027-05-17FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
The search for new anti-infectives increasingly looks to natural sources. However, producing and characterizing these compounds with clinical consistency rem...
One Health Biotechnology Approaches to Infectious Disease Pharmacology: Emerging Bioactive Agents for Antimicrobial and Vector-Borne Disease Control
Deadline 2027-05-17FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
The search for new anti-infectives increasingly looks to natural sources. However, producing and characterizing these compounds with clinical consistency rem...
Rational Design of Safer Bioactive Scaffolds: Integrating Synthesis, Pharmacology, and Computational Toxicity Prediction
Deadline 2027-05-17FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Balancing therapeutic potency with organ safety remains a central challenge in medicinal chemistry, particularly for drugs targeting inflammation, cancer, an...
Rational Design of Safer Bioactive Scaffolds: Integrating Synthesis, Pharmacology, and Computational Toxicity Prediction
Deadline 2027-05-17FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Balancing therapeutic potency with organ safety remains a central challenge in medicinal chemistry, particularly for drugs targeting inflammation, cancer, an...
RNA Therapeutics in Clinical Translation: Oligonucleotides and RNA-Targeted Small Molecules From Discovery to Approved Drugs
Deadline 2027-05-21FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
The past decade has transformed what a therapeutic molecule can be. mRNA, small interfering RNA (siRNA), and antisense oligonucleotide (ASO) drugs have moved...
RNA Therapeutics in Clinical Translation: Oligonucleotides and RNA-Targeted Small Molecules From Discovery to Approved Drugs
Deadline 2027-05-21FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
The past decade has transformed what a therapeutic molecule can be. mRNA, small interfering RNA (siRNA), and antisense oligonucleotide (ASO) drugs have moved...
Pharmacological Determinants of mRNA Vaccine Performance: RNA Chemistry, Lipid Nanoparticle Formulation, and Next-Generation Platforms
Deadline 2027-05-24FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
mRNA vaccines have moved from a largely theoretical platform to a clinically validated modality since the emergency authorizations of the first COVID-19 mRNA...
Pharmacological Determinants of mRNA Vaccine Performance: RNA Chemistry, Lipid Nanoparticle Formulation, and Next-Generation Platforms
Deadline 2027-05-24FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
mRNA vaccines have moved from a largely theoretical platform to a clinically validated modality since the emergency authorizations of the first COVID-19 mRNA...
Gut Microbiota as a Bridge: Deciphering the Mechanisms of Traditional Medicine through Microbiome-Metabolite Interactions
Deadline 2027-05-28FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Traditional medicines have long been valued for their therapeutic effects across a wide range of diseases, yet the precise molecular mechanisms underlying ma...
Gut Microbiota as a Bridge: Deciphering the Mechanisms of Traditional Medicine through Microbiome-Metabolite Interactions
Deadline 2027-05-28FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Traditional medicines have long been valued for their therapeutic effects across a wide range of diseases, yet the precise molecular mechanisms underlying ma...
Neuropharmacology of Alcohol Use Disorders
Deadline 2027-05-31FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Alcohol Use Disorder (AUD) remains a major global public health and socioeconomic challenge. Available pharmacotherapeutic agents show limited efficacy in re...
Neuropharmacology of Alcohol Use Disorders
Deadline 2027-05-31FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Alcohol Use Disorder (AUD) remains a major global public health and socioeconomic challenge. Available pharmacotherapeutic agents show limited efficacy in re...
Linking Human Pathophysiology with Advanced In Vitro Models for Regenerative and Delivery Focused Pharmacology
Deadline 2027-06-01FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Disease modeling is advancing alongside the broader adoption of New Approach Methodologies in biomedical research. Patient derived cells, induced pluripotent...
Linking Human Pathophysiology with Advanced In Vitro Models for Regenerative and Delivery Focused Pharmacology
Deadline 2027-06-01FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Disease modeling is advancing alongside the broader adoption of New Approach Methodologies in biomedical research. Patient derived cells, induced pluripotent...
Beyond Classical Monoamine Receptors: Emerging Regulators and Therapeutic Targets in Neuropharmacology
Deadline 2027-07-30FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Monoaminergic neurotransmission has traditionally been understood through the pharmacology of dopamine, serotonin, and adrenergic receptors. However, growing...
Beyond Classical Monoamine Receptors: Emerging Regulators and Therapeutic Targets in Neuropharmacology
Deadline 2027-07-30FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Monoaminergic neurotransmission has traditionally been understood through the pharmacology of dopamine, serotonin, and adrenergic receptors. However, growing...
Ethnopharmacology at 60: Sixty Years of Ethnopharmacology: From Local Knowledge to Global Recognition
Deadline 2027-09-30FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Ethnopharmacology can be traced to the interest in psychoactive and psychedelic substances in the 1960s; the term itself was first used in 1967 by Bo Holmste...
Ethnopharmacology at 60: Sixty Years of Ethnopharmacology: From Local Knowledge to Global Recognition
Deadline 2027-09-30FrontiersIndexed (Active)
Journal: Frontiers in Pharmacology
Ethnopharmacology can be traced to the interest in psychoactive and psychedelic substances in the 1960s; the term itself was first used in 1967 by Bo Holmste...
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