Recent Developments in Motor Neuron Disease: Pathophysiology, Diagnosis and Therapy
Journal: International Journal of General Medicine
Motor neuron disease (MND) is a heterogenous group of neurodegenerative, predominantly fatal or severely disabling disorders, affecting primarily upper and lower motor neurons. For decades MND was only partially understood with treatment options limited mainly to symptomatic therapies. Recent advances in mechanisms including specific genetic mutations gave exciting insights into pathophysiology of various forms of M…