Advances in Adoptive Cell Therapies
Journal: OncoImmunology
Adoptive cell therapies (ACT) have recently taken center stage in cancer immunotherapy, largely due to the success of chimeric antigen receptor (CAR-T) cell therapies in treating hematologic malignancies. In ACT, patient immune cells are collected, engineered ex vivo to strengthen anti-tumor immunity, expanded, and then infused back into the patient. From infusions of tumor-infiltrating lymphocytes (TIL) to the deveā¦